{"id":254,"date":"2023-09-29T12:42:41","date_gmt":"2023-09-29T12:42:41","guid":{"rendered":"https:\/\/inovandosites.com.br\/nefrocell\/?page_id=254"},"modified":"2023-09-29T12:42:41","modified_gmt":"2023-09-29T12:42:41","slug":"celulas-tronco","status":"publish","type":"page","link":"https:\/\/nefrocell.com.br\/index.php\/celulas-tronco\/","title":{"rendered":"CELULAS TRONCO"},"content":{"rendered":"\t\t
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C\u00e9lulas Tronco<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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O que s\u00e3o C\u00e9lulas Tronco?<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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As c\u00e9lulas-tronco s\u00e3o c\u00e9lulas indiferenciadas, ou seja, s\u00e3o c\u00e9lulas capazes de se transformar em outros tipos celulares com especialidades e fun\u00e7\u00f5es espec\u00edficas quando estimuladas. Estas c\u00e9lulas s\u00e3o encontradas em todos os indiv\u00edduos, desde a fase embrion\u00e1ria at\u00e9 a fase adulta.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Existem diferentes tipos de c\u00e9lulas-tronco, dentre elas, c\u00e9lulas-tronco embrion\u00e1rias, c\u00e9lulas-tronco mesenquimais, c\u00e9lulas-tronco hematopoi\u00e9ticas, entre outras. Na BIO CELL s\u00e3o utilizadas as c\u00e9lulas-tronco mesenquimais.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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Essas c\u00e9lulas est\u00e3o presentes em diversos tecidos do corpo e podem auxiliar no reparo de les\u00f5es do tecido no qual est\u00e3o localizadas, bem como realizar a substitui\u00e7\u00e3o de c\u00e9lulas que morrem naturalmente nos tecidos.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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Fraturas<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Condi\u00e7\u00f5es para a terapia celular:
1\u00ba A fratura precisa ser estabilizada;
2\u00ba Aus\u00eancia de Osteomielite;
3\u00ba Realizar a terapia celular com c\u00e9lulas-tronco antes da forma\u00e7\u00e3o de tecido fibroso;
4\u00ba Ser houver forma\u00e7\u00e3o de tecido fibroso associada com shockwave;
5\u00ba Aplica\u00e7\u00e3o das c\u00e9lulas-troco deve ocorrer no local da perda \u00f3ssea preenchendo todo o espa\u00e7o.
Vantagens:
\u2022 Diminui\u00e7\u00e3o do tempo de consolida\u00e7\u00e3o \u00f3ssea
\u2022 Melhor qualidade do tecido formado
\u2022 Diminui\u00e7\u00e3o do tempo de imobiliza\u00e7\u00e3o da fratura e\/ou repouso do animal
\u2022 Aus\u00eancia de efeito colateral<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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Osteartrose<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Condi\u00e7\u00f5es para a terapia celular:
1\u00ba 0 = normal;
2\u00ba Evid\u00eancias radiogr\u00e1ficos de instabilidade;
3\u00ba Altera\u00e7\u00e3o degenerativa (oste\u00f3fitos ocasionais);
4\u00ba Altera\u00e7\u00e3o degenerativa m\u00e9dia (oste\u00f3fitos e esclerose subcondral);
5\u00ba Altera\u00e7\u00e3o degenerativa severa (oste\u00f3fitos, esclerose subcondral e\/ou remodela\u00e7\u00e3o \u00f3ssea)
Vantagens:
\u2022 Diminui\u00e7\u00e3o ou revers\u00e3o do dano articular
\u2022 Melhora da viscosidade do l\u00edquido sinoval
\u2022 Aus\u00eancia de efeito colateral
\u2022 Redu\u00e7\u00e3o do desgante articular
\u2022 Diminui\u00e7\u00e3o da claudica\u00e7\u00e3o<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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\u00dalcera de C\u00f3rnea<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Condi\u00e7\u00f5es para a terapia celular:
1\u00ba Manter col\u00edrio lubrificante;
2\u00ba Manter uso de antibi\u00f3tico;
3\u00ba A primeira dose de c\u00e9lulas-tronco deve ser realizada, preferencialmente, via subconjuntival, seguida por aplica\u00e7\u00f5es t\u00f3picas em um per\u00edodo de 24 horas.
Vantagens:
\u2022 Dimuni\u00e7\u00e3o do tempo de cicatiza\u00e7\u00e3o
\u2022 Diminui\u00e7\u00e3o do processo inflamat\u00f3rio
\u2022 Aus\u00eancia de efeito colateral<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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Ceratoconjutivite seca CCS<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Condi\u00e7\u00f5es para a terapia celular:
1\u00ba Diagnosticar a causa do CCS. O uso das c\u00e9lulas -tronco em causas neurol\u00f3gicas deve ser avaliado com cautela;
2\u00ba Infec\u00e7\u00f5es secund\u00e1rias devem ser tratadas antes\/durante o tratamento com c\u00e9lulas-tronco;
3\u00ba O protocolo de tratamento \u00e9 de 3 aplica\u00e7\u00f5es com intervalo de 21 dias;
4\u00ba A aplica\u00e7\u00e3o das c\u00e9lulas-tronco deve ocorrer nas gl\u00e2ndulas lacrimais. Em casos mais severos considerar aplica\u00e7\u00e3o IV.
Vantagens:
\u2022 Aumento da produ\u00e7\u00e3o lacrimal
\u2022 Diminui\u00e7\u00e3o da inflama\u00e7\u00e3o ocular
\u2022 Aus\u00eancia de efeito colateral
\u2022 Ativa\u00e7\u00e3o de c\u00e9lulas produtoras de mucina da l\u00e1grima<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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Feridas<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Condi\u00e7\u00f5es para a terapia celular:
1\u00ba As causas base para a n\u00e3o cicatriza\u00e7\u00e3o devem ser investigadas, como por exemplo, diabetes e hipotireodismo (c\u00e3es\/gatos0 e Habromenose (equinos);
2\u00ba Avaliar a presen\u00e7a de infec\u00e7\u00e3o bacteriana ou fungica na pele e realizar o tratamento, o qual n\u00e3o precisa ser surpreso para a realiza\u00e7\u00e3o da terapia celular;
3\u00ba O n\u00famero de aplica\u00e7\u00f5es depende da da extens\u00e3o da les\u00e3o e o intervalo entre deve ser no m\u00e1ximo 21 dias.
Vantagens:
\u2022 Diminui\u00e7\u00e3o da forma\u00e7\u00e3o do tecido de granula\u00e7\u00e3o
\u2022 Dimuni\u00e7\u00e3o do tempo de cicatriza\u00e7\u00e3o<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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Sequela Neurol\u00f3gica da Cinomose<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Condi\u00e7\u00f5es para a terapia celular:
1\u00ba Erlichiose em caninos \/ Hiperestrogenismo
2\u00ba Leishmaniose \/ Anemias hemol\u00edticas autoimunes
3\u00ba Micoplasmose em felinos \/ FIV e FeLV em felinos
Vantagens:
\u2022 Repopula\u00e7\u00e3o da medula \u00f3ssea
\u2022 Promove diferencia\u00e7\u00e3o em c\u00e9lulas-tronco hematopoi\u00e9ticas, liberam citocinas e fatores de crescimento
\u2022 Imunomodula\u00e7\u00e3o
\u2022 Aus\u00eancia de efeitos colaterais<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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Doen\u00e7a Renal Cr\u00f4nica<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Condi\u00e7\u00f5es para a terapia celular:
1\u00ba Estadiamento da DRC (melhores resultados at\u00e9 IRIS 3);
2\u00ba Realizar exames: hemograma, ur\u00e9ia, creatina, urin\u00e1lise, ultrassonografia;
3\u00ba Aferir press\u00e3o arterial e tratar caso necess\u00e1rio;
4\u00ba Protocolo de 3 aplica\u00e7\u00f5es com intervalo de 21 dias entre cada aplica\u00e7\u00e3o;
5\u00ba Avaliar a necessidade de corrigir a desidrata\u00e7\u00e3o e acidose metab\u00f3lica.
Vantagens:
\u2022 Melhora de apetite
\u2022 Aus\u00eancia de efeito colateral
\u2022 Renoprote\u00e7\u00e3o \/ Neovascula\u00e7\u00e3o
\u2022 Maior disposi\u00e7\u00e3o, diminui\u00e7\u00e3o de v\u00f4mitos e ganho de peso<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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Hipoplasia de Medula \u00d3ssea<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Condi\u00e7\u00f5es para a terapia celular:
1\u00ba Erlichiose em caninos \/ Hiperestrogenismo
2\u00ba Leishmaniose \/ Anemias hemol\u00edticas autoimunes
3\u00ba Micoplasmose em felinos \/ FIV e FeLV em felinos
Vantagens:
\u2022 Repopula\u00e7\u00e3o da medula \u00f3ssea
\u2022 Promove diferencia\u00e7\u00e3o em c\u00e9lulas-tronco hematopoi\u00e9ticas, liberam citocinas e fatores de crescimento
\u2022 Imunomodula\u00e7\u00e3o
\u2022 Aus\u00eancia de efeitos colaterais<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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Discopatias<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Condi\u00e7\u00f5es para a terapia celular:
1\u00ba O diagn\u00f3stico deve ser realizado via tomografia ou resson\u00e2ncia magn\u00e9tica;
2\u00ba A aplica\u00e7\u00e3o \u00e9 realizada preferencialmente no espa\u00e7o epidural, quando j\u00e1 se passaram mais de 30 dias de les\u00e3o;
3\u00ba A aplica\u00e7\u00e3o de c\u00e9lulas-tronco n\u00e3o substitui o procedimento cir\u00fargico. Aplica\u00e7\u00e3o no transoperat\u00f3rio aumenta em 26% a taxa de sucesso cir\u00fargico (Kim et al., 2016);
4\u00ba O tempo ocorrido de les\u00e3o deve ser considerado em rela\u00e7\u00e3o \u00e0 expectativa de resultados;
Vantagens:
\u2022 Retorno a deambula\u00e7\u00e3o
\u2022 Imunomodula\u00e7\u00e3o e suporte a remieliniza\u00e7\u00e3o<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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Dermatite at\u00f3pica<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Condi\u00e7\u00f5es para a terapia celular:
1\u00ba Avaliar a presen\u00e7a de infec\u00e7\u00e3o bacteriana ou fungica na pele e realizar o tratamento, o qual n\u00e3o precisa ser suspenso para a realiza\u00e7\u00e3o da terapia celular;
2\u00ba O protecolo padr\u00e3o \u00e9 de tr\u00eas aplica\u00e7\u00f5es com intervalo de 21 dias entre elas;
3\u00ba A aplica\u00e7\u00e3o das c\u00e9lulas-tronco deve ser realizada via intravenosa e\/ou intrad\u00e9rmica dependendo das caracter\u00edsticas das les\u00f5es.
Vantagens:
\u2022 Melhora cl\u00ednica sem efeitos colaterais
\u2022 Diminui\u00e7\u00e3o do processo inflamat\u00f3rio da pele
\u2022 Diminui\u00e7\u00e3o do prurido<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\"\"\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Equinos e Bovinos<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Equinos:
\u2022 Tendinopatias
\u2022 Feridas
\u2022 Fraturas
\u2022 Endomstrites
\u2022 Osteoartroses<\/p>

Bovinos:
\u2022 Les\u00f5es ovarianas (bovinos)<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

\n\t\t\t
\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

C\u00e9lulas Tronco O que s\u00e3o C\u00e9lulas Tronco? As c\u00e9lulas-tronco s\u00e3o c\u00e9lulas indiferenciadas, ou seja, s\u00e3o c\u00e9lulas capazes de se transformar em outros tipos celulares com especialidades e fun\u00e7\u00f5es espec\u00edficas quando estimuladas. Estas c\u00e9lulas s\u00e3o encontradas em todos os indiv\u00edduos, desde a fase embrion\u00e1ria at\u00e9 a fase adulta. Existem diferentes tipos de c\u00e9lulas-tronco, dentre elas, c\u00e9lulas-tronco […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"","ast-site-content-layout":"full-width-container","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-254","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/nefrocell.com.br\/index.php\/wp-json\/wp\/v2\/pages\/254","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nefrocell.com.br\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/nefrocell.com.br\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/nefrocell.com.br\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/nefrocell.com.br\/index.php\/wp-json\/wp\/v2\/comments?post=254"}],"version-history":[{"count":0,"href":"https:\/\/nefrocell.com.br\/index.php\/wp-json\/wp\/v2\/pages\/254\/revisions"}],"wp:attachment":[{"href":"https:\/\/nefrocell.com.br\/index.php\/wp-json\/wp\/v2\/media?parent=254"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}